TOF/TOF™ 5800 System

///TOF/TOF™ 5800 System
  • TOF/TOF™ 5800 System

TOF/TOF™ 5800 System

The TOF/TOF 5800 System provides the fastest and most confident path to identification and relative quantitation of proteins. The system’s unmatched speed and sensitivity make it the ideal platform for biomarker discovery, MALDI mass spectrometry imaging, and protein identification.

  • More than 10-fold faster data acquisition with new 1 KHz laser and DynamicExit™ Algorithm
  • Unique OptiBeam On-axis Laser irradiation increases sensitivity in both MS and MS/MS modes by 10-fold over systems without an on-axis laser
  • Maximum up-time and throughput by continuously heating of the source mirror and user-programmable source mirror cleaning
  • Improved resolution with new reflectron mirror design and 1000 MHz digitizer
  • High-resolution precursor ion selection with novel timed-ion selector

Product Description


More than 10-fold faster acquisition:  The new 1 kHz laser provides lightning-fast ionization, and the innovative DynamicExit™ Algorithm provides highest-confidence IDs with the fewest number of laser shots. Now, there is an LC/MALDI-TOF/TOF system with an analysis speed that rivals that of ESI/MS/MS.


Figure 1: The TOF/TOF 5800 System continues our legacy of technical innovation in mass spectrometry.
SCIEX TOF/TOF™ 5800 System Continues Our Legacy of Technical Innovation in Mass Spectrometry.
Figure 2: TOF/TOF 5800 System is more than 10-times faster than previous systems.

Easier to use

The new EasyAccess™ Wizard provides a single-page interface that quickly guides users through the set-up of acquisition parameters. Simple to use but powerful, ProteinPilot™ Software 4.0 is complemented by application-specific software to ensure that getting meaningful results is fast and easy.
Longer continuous run times

 A user-programmable routine decontaminates the MALDI source to remove matrix deposits, and the heated source mirror is continually cleaned. There’s no more need to break your experimental sequence to keep the instrument running optimally.

Ideal system for reagents

The 5800 System is designed to provide the highest sensitivity and most reproducible results from isobaric-tagging workflows. No modifications or add-ons are required to achieve optimal results.

See information that you’ve been missing

Electrospray mass spectrometers only give you part of the picture. MALDI TOF/TOF data is a perfect compliment to ESI data for more comprehensive, in-depth identification and relative quantitation of proteins in complex samples.

Get the greatest depth of coverage with the LC MALDI workflow

The LC MALDI workflow separates the time constraints of LC from the mass analysis. With your chromatographic run “stored” on a MALDI plate, you can spend as much time as required to get the maximum information from a given region or time point.


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